Actin cytoskeleton–dependent regulation of corticotropin-releasing factor receptor heteromers
نویسندگان
چکیده
منابع مشابه
Actin cytoskeleton–dependent regulation of corticotropin-releasing factor receptor heteromers
Stress responses are highly nuanced and variable, but how this diversity is achieved by modulating receptor function is largely unknown. Corticotropin-releasing factor receptors (CRFRs), class B G protein-coupled receptors, are pivotal in mediating stress responses. Here we show that the two known CRFRs interact to form heteromeric complexes in HEK293 cells coexpressing both CRFRs and in vivo i...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2017
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.e16-11-0778